A handwritten note

I must get rid of all those that stand in the way of my research. Even that man from the Turks. I scientifically altered him and put him in the basement. If you want to find him, then search the area. But, this is merely a game I thought of.  It is not necessary for you to participate if you don't want to. The safe is voice activated.  Speak the combination carefully and in the correct order.  The four hints for
the numbers are:

1. The lid of the box with the most oxygen.
2. Behind the ivorys short of tea and ray.
3. The creak in the floor near the chair on the second floor.
4. Right 78